Buy Xipere (triamcinolone acetonide injectable suspension)

What is Xipere (triamcinolone acetonide injectable suspension) for?

Xipere (triamcinolone acetonide injectable suspension) is a corticosteroid indicated for suprachoroidal use for the treatment of macular edema associated with uveitis, a form of eye inflammation.^[1]

It is available in vial form and comes with a syringe, containing 40 mg/mL triamcinolone acetonide injectable suspension.^[1]

How does Xipere (triamcinolone acetonide injectable suspension) work?

Macular edema occurs when fluid accumulates in the macula, a region of the center of the retina. This causes swelling, which distorts vision. It can be one of the symptoms of uveitis, a form of eye inflammation.^[2]

The active ingredient in Xipere, triamcinolone acetonide, is a corticosteroid, an anti-inflammatory drug. By blocking inflammation, it can reduce uveitis and thus macular edema.3

Xipere is injected into the suprachoroidal space (SCS). The SCS is located between the sclera – the outermost layer that forms the white part of your eye – and the choroid, the underlying layer which contains the blood vessels that nourish the retina. By injecting in the SCS, Xipere can reach the back of the eye precisely.3

Where has Xipere (triamcinolone acetonide injectable suspension) been approved?

Xipere (triamcinolone acetonide injectable suspension) was approved for the treatment of macular edema associated with uveitis by:4

• The Food and Drug Administration (FDA), USA on October 25, 2021.

Please note that this medicine may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.

How is Xipere (triamcinolone acetonide injectable suspension) taken?

The standard dosage is:^[1]

• 4 mg (0.1 mL) administered as an injection into the suprachoroidal space (SCS)

The injection is given by a trained healthcare professional using the SCS Microinjector®, which is designed for precise injection directly into the SCS.^[1]

Complete information about Xipere (triamcinolone acetonide injectable suspension) dosage and administration can be found in the official prescribing information listed in our references section.^[1]

Note: Please consult with your treating doctor for personalised dosing.

Are there any known adverse reactions or side effects of Xipere (triamcinolone acetonide injectable suspension)?

Common adverse reactions

The most common side effects (≥10% of patients) listed in the prescribing information include:^[1]

• Increased ocular pressure
• Eye pain

Use in a specific population

Xipere (triamcinolone acetonide injectable suspension) is not recommended for use in patients with:

• Active or suspected ocular or periocular infections including most viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, mycobacterial infections, and fungal diseases.
• Known hypersensitivity to triamcinolone acetonide or any other components of Xipere

For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.^[1]

References

1. Full prescribing information [FDA]: Xipere (triamcinolone acetonide injectable suspension) [PDF]
Incyte, Sep 2021

2. Macular Edema
ASRS.org, cited Jan 2022

3. Suprachoroidal space
Xipere.com, cited Jan 2022

4. Bausch + Lomb and Clearside Biomedical Announce FDA Approval of XIPERE™ (triamcinolone acetonide injectable suspension) for Suprachoroidal Use for the Treatment of Macular Edema Associated with Uveitis
Clearside press release, Oct 2021